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KRT19 / CK19 / Cytokeratin 19 Antibody (clone RCK108)

Mouse Monoclonal Antibody

     
  • IHC - KRT19 / CK19 / Cytokeratin 19 Antibody (clone RCK108) ALS14873
    Anti-Cytokeratin 19 antibody IHC of human lung.
    detail
  • SPECIFICATION
  • CITATIONS: 1
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC, FC, IHC-F
Primary Accession P08727
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names RCK108
Calculated MW 44kDa
Dilution Flo (1:100-1:200), IHC-Fr (1:100-1:200), IHC-P (10 µg/ml), WB (1:100-1:1000) ,
Additional Information
Gene ID 3880
Other Names Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19, KRT19
Target/Specificity Reacts exclusively with cytokeratin 19 which is present in glandular-type epithelia and most carcinomas. Does not react with hepatocytes and hepatocellular carcinoma.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsKRT19 / CK19 / Cytokeratin 19 Antibody (clone RCK108) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT19
Function Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Tissue Location Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
Volume Array
Research Areas
Citations ( 0 )

Background

Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

References

Stasiak P.C.,et al.Nucleic Acids Res. 15:10058-10058(1987).
Bader B.L.,et al.Eur. J. Cell Biol. 47:300-319(1988).
Eckert R.L.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:1114-1118(1988).
Stasiak P.C.,et al.J. Invest. Dermatol. 92:707-716(1989).
Whittock N.V.,et al.Biochem. Biophys. Res. Commun. 267:462-465(2000).

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$ 565.00
Cat# ALS14873
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