Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
KRT7 / CK7 / Cytokeratin 7 Antibody (clone RCK105)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, ICC, IHC-F, FC |
|---|---|
| Primary Accession | P08729 |
| Reactivity | Human, Mouse, Rat, Hamster, Pig, Dog, Cat |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | RCK105 |
| Calculated MW | 51kDa |
| Dilution | Flo (1:100-1:200), IHC-Fr (1:100-1:200), IHC-P (10 µg/ml), WB (1:100-1:1000) , |
| Gene ID | 3855 |
|---|---|
| Other Names | Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Sarcolectin, Type-II keratin Kb7, KRT7, SCL |
| Target/Specificity | Reacts exclusively with cytokeratin 7 which is present in a subgroup of glandular epithelia and their tumors, as well as transitional epithelium and transitional carcinoma. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | KRT7 / CK7 / Cytokeratin 7 Antibody (clone RCK105) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KRT7 |
|---|---|
| Synonyms | SCL |
| Function | Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
References
Glass C.,et al.J. Cell Biol. 101:2366-2373(1985).
Glass C.,et al.J. Cell Biol. 107:1337-1350(1988).
Kaba A.,et al.Biochimie 81:709-715(1999).
Smith F.J.D.,et al.Biochem. Biophys. Res. Commun. 297:818-827(2002).
Scherer S.E.,et al.Nature 440:346-351(2006).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
