VAV2 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P52735 |
Reactivity | Human, Mouse, Rat, Hamster, Monkey, Pig, Horse, Bovine, Dog |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 101kDa |
Dilution | ELISA (1:32000), IHC-P (2.5-3.75 µg/ml), WB (1-1.5 µg/ml) |
Gene ID | 7410 |
---|---|
Other Names | Guanine nucleotide exchange factor VAV2, VAV-2, VAV2 |
Target/Specificity | Human VAV2. This antobody is expected to recognise both reported isoforms (NP_001127870.1 and NP_003362.2). |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | VAV2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | VAV2 |
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Function | Guanine nucleotide exchange factor for the Rho family of Ras- related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). |
Tissue Location | Widely expressed. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity).
References
Henske E.P.,et al.Ann. Hum. Genet. 59:25-37(1995).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Mancini U.M.,et al.Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
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