WISP2 Antibody (clone 1E11)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, E |
---|---|
Primary Accession | O76076 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 1E11 |
Calculated MW | 27kDa |
Dilution | IHC-P (5 µg/ml), WB (1:500-1:1000), |
Gene ID | 8839 |
---|---|
Other Names | WNT1-inducible-signaling pathway protein 2, WISP-2, CCN family member 5, Connective tissue growth factor-like protein, CTGF-L, Connective tissue growth factor-related protein 58, WISP2, CCN5, CT58, CTGFL |
Target/Specificity | Human WISP2 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | WISP2 Antibody (clone 1E11) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CCN5 (HGNC:12770) |
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Synonyms | CT58, CTGFL, WISP2 |
Function | May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production. |
Cellular Location | Secreted. |
Tissue Location | Expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart |

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Background
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
References
Kumar S.,et al.J. Biol. Chem. 274:17123-17131(1999).
Rowles J.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
Pennica D.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:14717-14722(1998).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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