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GSTA1 Antibody (clone 2F7)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P08263 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2F7 |
| Calculated MW | 26kDa |
| Dilution | IHC-P (5 µg/ml), WB (1:500-1:1000), |
| Gene ID | 2938 |
|---|---|
| Other Names | Glutathione S-transferase A1, 2.5.1.18, GST HA subunit 1, GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1, Glutathione S-transferase A1, N-terminally processed, GSTA1 |
| Target/Specificity | Human GSTA1 |
| Reconstitution & Storage | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
| Precautions | GSTA1 Antibody (clone 2F7) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GSTA1 |
|---|---|
| Function | Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene- 3,17-dione and may therefore play an important role in hormone biosynthesis (PubMed:11152686). Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)- hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid (PubMed:16624487). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Liver. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
References
Tu C.-P.D.,et al.Biochem. Biophys. Res. Commun. 141:229-237(1986).
Rhoads D.M.,et al.Biochem. Biophys. Res. Commun. 145:474-481(1987).
Tu C.-P.D.,et al.Biochem. Soc. Trans. 15:734-736(1987).
Board P.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:2377-2381(1987).
Rozen F.,et al.Arch. Biochem. Biophys. 292:589-593(1992).
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