CDH17 / Cadherin 17 Antibody (clone 1H3)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q12864 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 1H3 |
Calculated MW | 92kDa |
Dilution | IHC-P (5 µg/ml), WB (1:500-1:1000), |
Gene ID | 1015 |
---|---|
Other Names | Cadherin-17, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin, LI-cadherin, CDH17 |
Target/Specificity | Human CDH17 |
Reconstitution & Storage | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
Precautions | CDH17 / Cadherin 17 Antibody (clone 1H3) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CDH17 |
---|---|
Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.
References
Dantzig A.H.,et al.Science 264:430-433(1994).
Boettinger A.,et al.Submitted (DEC-1994) to the EMBL/GenBank/DDBJ databases.
Nusbaum C.,et al.Nature 439:331-335(2006).
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