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NPRB / NPR2 Antibody (clone 2A6)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P20594 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2A6 |
| Calculated MW | 117kDa |
| Dilution | IHC-P (5 µg/ml) |
| Gene ID | 4882 |
|---|---|
| Other Names | Atrial natriuretic peptide receptor 2, 4.6.1.2, Atrial natriuretic peptide receptor type B, ANP-B, ANPR-B, NPR-B, Guanylate cyclase B, GC-B, NPR2, ANPRB |
| Target/Specificity | Human NPR2 |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | NPRB / NPR2 Antibody (clone 2A6) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NPR2 |
|---|---|
| Synonyms | ANPRB |
| Function | Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.
References
Chang M.S.,et al.Nature 341:68-72(1989).
Rehemudula D.,et al.Circ. Res. 84:605-610(1999).
Hirsch J.R.,et al.J. Am. Soc. Nephrol. 10:472-480(1999).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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