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Mannose Receptor / CD206 Antibody (clone 5C11)

Mouse Monoclonal Antibody

     
  • WB - Mannose Receptor / CD206 Antibody (clone 5C11) ALS14104
    MRC1 monoclonal antibody clone 5C11. Western blot of MRC1 expression in human pancreas.
    detail
  • IHC - Mannose Receptor / CD206 Antibody (clone 5C11) ALS14104
    Anti-CD206 antibody IHC of human lung, macrophages.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P22897
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 5C11
Calculated MW 166kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:1000),
Additional Information
Gene ID 4360
Other Names Macrophage mannose receptor 1, MMR, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, Macrophage mannose receptor 1-like protein 1, CD206, MRC1, CLEC13D, CLEC13DL, MRC1L1
Target/Specificity Human MRC1
Reconstitution & Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMannose Receptor / CD206 Antibody (clone 5C11) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MRC1
Synonyms CLEC13D, CLEC13DL, MRC1L1
Function Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E.
Cellular Location Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)
citation

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Background

Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.

References

Taylor M.E.,et al.J. Biol. Chem. 265:12156-12162(1990).
Ezekowitz R.A.,et al.J. Exp. Med. 172:1785-1794(1990).
Kim S.J.,et al.Genomics 14:721-727(1992).
Deloukas P.,et al.Nature 429:375-381(2004).
Taylor M.E.,et al.J. Biol. Chem. 267:1719-1726(1992).

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$ 533.50
Cat# ALS14104
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