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PCSK1 Antibody (clone 3D2)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | P29120 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 3D2 |
| Calculated MW | 84kDa |
| Dilution | IF (30 µg/ml), IHC-P (10 µg/ml), WB (1:500-1:1000) |
| Gene ID | 5122 |
|---|---|
| Other Names | Neuroendocrine convertase 1, NEC 1, 3.4.21.93, Prohormone convertase 1, Proprotein convertase 1, PC1, PCSK1, NEC1 |
| Target/Specificity | Human PCSK1 |
| Reconstitution & Storage | Store at -20°C |
| Precautions | PCSK1 Antibody (clone 3D2) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PCSK1 |
|---|---|
| Synonyms | NEC1 |
| Function | Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP. |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.
References
Creemers J.W.M.,et al.FEBS Lett. 300:82-88(1992).
Seidah N.G.,et al.DNA Cell Biol. 11:283-289(1992).
Ohagi S.,et al.Diabetes 45:897-901(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
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