TNNT2 / CTNT Antibody
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P, E |
---|---|
Primary Accession | P45379 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Calculated MW | 36kDa |
Dilution | IHC-P (10 µg/ml) |
Gene ID | 7139 |
---|---|
Other Names | Troponin T, cardiac muscle, TnTc, Cardiac muscle troponin T, cTnT, TNNT2 |
Target/Specificity | Human cardiac Troponin T 100% Human skeletal Troponin T 0 %. |
Reconstitution & Storage | Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. |
Precautions | TNNT2 / CTNT Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TNNT2 |
---|---|
Function | Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
Tissue Location | Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart |

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Provided below are standard protocols that you may find useful for product applications.
Background
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
References
Mesnard L.,et al.FEBS Lett. 328:139-144(1993).
Townsend P.J.,et al.Genomics 21:311-316(1994).
Townsend P.J.,et al.J. Mol. Cell. Cardiol. 27:2223-2236(1995).
Anderson P.A.,et al.Circ. Res. 76:681-686(1995).
Mesnard L.,et al.Circ. Res. 76:687-692(1995).

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