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FH / Fumarase / MCL Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P07954 |
| Reactivity | Human, Mouse, Rat, Zebrafish, Hamster, Monkey, Pig, Chicken, Sheep, Horse, Xenopus, Bovine, Dog, Drosophila |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 55kDa |
| Dilution | ELISA (1:64000), IHC-P (3.75 µg/ml), |
| Gene ID | 2271 |
|---|---|
| Other Names | Fumarate hydratase, mitochondrial, Fumarase, 4.2.1.2, FH |
| Target/Specificity | Human FH / Fumarate hydratase. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | FH / Fumarase / MCL Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FH {ECO:0000303|PubMed:27037871, ECO:0000312|HGNC:HGNC:3700} |
|---|---|
| Function | Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (PubMed:30761759). Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable). |
| Cellular Location | [Isoform Mitochondrial]: Mitochondrion |
| Tissue Location | Expressed in red blood cells; underexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Also acts as a tumor suppressor.
References
Gellera C.,et al.Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases.
Bourgeron T.,et al.Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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