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FH / Fumarase / MCL Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - FH / Fumarase / MCL Antibody (Internal) ALS13701
    Antibody (0.01 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer).
    detail
  • IHC - FH / Fumarase / MCL Antibody (Internal) ALS13701
    Anti-FH / Fumarase antibody IHC of human heart.
    detail
  • IHC - FH / Fumarase / MCL Antibody (Internal) ALS13701
    Anti-FH / Fumarase antibody IHC of human skeletal muscle.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P07954
Reactivity Human, Mouse, Rat, Zebrafish, Hamster, Monkey, Pig, Chicken, Sheep, Horse, Xenopus, Bovine, Dog, Drosophila
Host Goat
Clonality Polyclonal
Calculated MW 55kDa
Dilution ELISA (1:64000), IHC-P (3.75 µg/ml),
Additional Information
Gene ID 2271
Other Names Fumarate hydratase, mitochondrial, Fumarase, 4.2.1.2, FH
Target/Specificity Human FH / Fumarate hydratase.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsFH / Fumarase / MCL Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FH {ECO:0000303|PubMed:27037871, ECO:0000312|HGNC:HGNC:3700}
Function Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (PubMed:30761759). Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable).
Cellular Location [Isoform Mitochondrial]: Mitochondrion
Tissue Location Expressed in red blood cells; underexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology.
Research Areas
Citations (0)
citation

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Background

Also acts as a tumor suppressor.

References

Gellera C.,et al.Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases.
Bourgeron T.,et al.Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 467.50
Cat# ALS13701
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