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FLOT2 / Flotillin 2 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • WB - FLOT2 / Flotillin 2 Antibody (C-Terminus) ALS13691
    FLOT2 antibody (0.1 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein/ml in RIPA...
    detail
  • IHC - FLOT2 / Flotillin 2 Antibody (C-Terminus) ALS13691
    Anti-FLOT2 / Flotillin 1 antibody IHC of human tonsil.
    detail
  • SPECIFICATION
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q14254
Reactivity Human, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 47kDa
Dilution ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml)
Additional Information
Gene ID 2319
Other Names Flotillin-2, Epidermal surface antigen, ESA, Membrane component chromosome 17 surface marker 1, FLOT2, ESA1, M17S1
Target/Specificity Human FLOT2 / Flotillin 1.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsFLOT2 / Flotillin 2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FLOT2
Synonyms ESA1, M17S1
Function May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
Cellular Location Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Endosome Membrane; Lipid-anchor. Note=Membrane- associated protein of caveolae
Tissue Location In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes
Research Areas
Citations (0)
citation

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Background

May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.

References

Zody M.C.,et al.Nature 440:1045-1049(2006).
Schroeder W.T.,et al.J. Biol. Chem. 269:19983-19991(1994).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Gorbea C.,et al.J. Biol. Chem. 285:31616-31633(2010).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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$ 467.50
Cat# ALS13691
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