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Complement C9 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, ICC |
|---|---|
| Primary Accession | P02748 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 63kDa |
| Dilution | ICC (1:100-1:200), IF (1:100-1:200), IHC-P (10 µg/ml), WB (1:500-1:3000) , |
| Gene ID | 735 |
|---|---|
| Other Names | Complement component C9, Complement component C9a, Complement component C9b, C9 |
| Target/Specificity | Human Complement C9. |
| Reconstitution & Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| Precautions | Complement C9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | C9 |
|---|---|
| Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells (PubMed:26841934, PubMed:9212048, PubMed:9634479). C9 is the pore-forming subunit of the MAC (PubMed:26841934, PubMed:30111885, PubMed:4055801). |
| Cellular Location | Secreted. Target cell membrane; Multi-pass membrane protein. Note=Secreted as soluble monomer Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore |
| Tissue Location | Plasma (at protein level). |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
References
Stanley K.K.,et al.EMBO J. 4:375-382(1985).
Discipio R.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 81:7298-7302(1984).
Marazziti D.,et al.Biochemistry 27:6529-6534(1988).
Witzel-Schloemp K.,et al.Immunogenetics 48:144-147(1998).
DiScipio R.G.,et al.J. Biol. Chem. 260:14802-14809(1985).
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