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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IDH1 / IDH Antibody   

IDH1 / IDH Antibody

Rabbit Polyclonal Antibody

     
  • WB - IDH1 / IDH Antibody ALS13644
    Sample(30 ug whole cell lysate). A: A431. B: Raji. 10% SDS PAGE. IDH1 antibody diluted at 1:1000.
    detail
  • IHC - IDH1 / IDH Antibody ALS13644
    Anti-IDH1 antibody IHC of human liver.
    detail
  • IHC - IDH1 / IDH Antibody ALS13644
    Anti-IDH1 antibody IHC of human prostate.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession O75874
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 47kDa
Dilution IHC-P (10 µg/ml), WB (1:500-1:3000),
Additional Information
Gene ID 3417
Other Names Isocitrate dehydrogenase [NADP] cytoplasmic, IDH, 1.1.1.42, Cytosolic NADP-isocitrate dehydrogenase, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, IDH1, PICD
Target/Specificity Human IDH1. Predicted cross-reactivity based on amino acid sequence homology: mouse (96%), rat (97%), bovine (95%), zebrafish (85%).
Reconstitution & Storage Aliquot and store at -20°C. Minimize freezing and thawing.
PrecautionsIDH1 / IDH Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IDH1
Synonyms PICD
Function Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase (PubMed:10521434, PubMed:19935646). Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways (PubMed:10521434). May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency (By similarity).
Cellular Location Cytoplasm, cytosol. Peroxisome
Volume 50 µl
Research Areas
Citations (0)
citation

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References

Nekrutenko A.,et al.Mol. Biol. Evol. 15:1674-1684(1998).
Geisbrecht B.V.,et al.J. Biol. Chem. 274:30527-30533(1999).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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$ 467.50
Cat# ALS13644
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