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ARG1 / Arginase 1 Antibody

Rabbit Polyclonal Antibody

     
  • WB - ARG1 / Arginase 1 Antibody ALS13619
    Sample (30 ug of whole cell lysate).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P05089
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 35kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:3000),
Additional Information
Gene ID 383
Other Names Arginase-1, 3.5.3.1, Liver-type arginase, Type I arginase, ARG1
Target/Specificity Human Arginase I. Predicted cross-reactivity based on amino acid sequence homology: mouse (85%), rat (83%), rabbit (90%), bovine (89%), pig (90%).
Reconstitution & Storage Aliquot and store at -20°C. Minimize freezing and thawing.
PrecautionsARG1 / Arginase 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARG1
Function Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.
Cellular Location Cytoplasm. Cytoplasmic granule. Note=Localized in azurophil granules of neutrophils (PubMed:15546957)
Tissue Location Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]) (PubMed:15546957). Also detected in macrophages mycobacterial granulomas (PubMed:23749634). Expressed in group2 innate lymphoid cells (ILC2s) during lung disease (PubMed:27043409)
Volume 50 µl
Research Areas
Citations (0)
citation

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References

Haraguchi Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:412-415(1987).
Takiguchi M.,et al.Nucleic Acids Res. 16:8789-8802(1988).
Lee Y.T.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).

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$ 467.50
Cat# ALS13619
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