TGF-Beta Antibody (clone TB21)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E, IHC-F, Neut, FuncS |
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Primary Accession | P01137 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | TB21 |
Calculated MW | 44325 Da |
Dilution | IHC-P (10 µg/ml) |
Gene ID | 7040 |
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Other Names | Transforming growth factor beta-1, TGF-beta-1, Latency-associated peptide, LAP, TGFB1, TGFB |
Target/Specificity | Recognizes both human platelet-derived and recombinant TGF-beta. |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | TGF-Beta Antibody (clone TB21) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TGFB1 (HGNC:11766) |
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Synonyms | TGFB |
Function | Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. |
Cellular Location | [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix |
Tissue Location | Highly expressed in bone (PubMed:11746498, PubMed:17827158). Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA) (PubMed:11746498, PubMed:17827158). Colocalizes with ASPN in chondrocytes within OA lesions of articular cartilage (PubMed:17827158) |
Volume | 250 µl |
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