CARD10 / CARMA3 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q9BWT7 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 116kDa |
Dilution | IHC-P (5 µg/ml) |
Gene ID | 29775 |
---|---|
Other Names | Caspase recruitment domain-containing protein 10, CARD-containing MAGUK protein 3, Carma 3, CARD10, CARMA3 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | CARD10 / CARMA3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CARD10 |
---|---|
Synonyms | CARMA3 |
Function | Scaffold protein that plays an important role in mediating the activation of NF-kappa-B via BCL10 or EGFR. |
Cellular Location | Cytoplasm. |
Tissue Location | Detected in adult heart, kidney and liver; lower levels in intestine, placenta, muscle and lung. Also found in fetal lung, liver and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
Activates NF-kappa-B via BCL10 and IKK.
References
Wang L.,et al.J. Biol. Chem. 276:21405-21409(2001).
Gaide O.,et al.FEBS Lett. 496:121-127(2001).
Gaide O.,et al.FEBS Lett. 505:198-198(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham I.,et al.Nature 402:489-495(1999).
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