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FTL / Ferritin Light Chain Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P02792 |
| Reactivity | Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Horse, Bovine, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 20kDa |
| Dilution | ELISA (1:4000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml) |
| Gene ID | 2512 |
|---|---|
| Other Names | Ferritin light chain, Ferritin L subunit, FTL |
| Target/Specificity | Human FTL. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | FTL / Ferritin Light Chain Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FTL |
|---|---|
| Function | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes by the cargo receptor NCOA4 for autophagic degradation and release or iron (PubMed:24695223). |
| Cellular Location | Cytoplasmic vesicle, autophagosome. Cytoplasm {ECO:0000250|UniProtKB:P29391}. Autolysosome {ECO:0000250|UniProtKB:P29391} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
References
Boyd D.,et al.J. Biol. Chem. 260:11755-11761(1985).
Dorner M.H.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:3139-3143(1985).
Santoro C.,et al.Nucleic Acids Res. 14:2863-2876(1986).
Jordan T.P.,et al.Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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