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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TIMP2 Antibody (clone 3A4)   

TIMP2 Antibody (clone 3A4)

Mouse Monoclonal Antibody

     
  • IHC - TIMP2 Antibody (clone 3A4) ALS13261
    Anti-TIMP2 antibody IHC of human adrenal.
    detail
  • IHC - TIMP2 Antibody (clone 3A4) ALS13261
    Anti-TIMP2 antibody IHC of human liver.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P16035
Reactivity Human, Mouse, Rabbit, Zebrafish, Pig, Chicken
Host Mouse
Clonality Monoclonal
Clone Names 3A4
Calculated MW 24kDa
Dilution IHC-P (5-10 µg/ml)
Additional Information
Gene ID 7077
Other Names Metalloproteinase inhibitor 2, CSC-21K, Tissue inhibitor of metalloproteinases 2, TIMP-2, TIMP2
Reconstitution & Storage Long term: -20°C; Short term: -20°C
PrecautionsTIMP2 Antibody (clone 3A4) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TIMP2
Function Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
Cellular Location Secreted.
Research Areas
Citations (0)
citation

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Background

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

References

Stetler-Stevenson W.G.,et al.J. Biol. Chem. 265:13933-13938(1990).
Boone T.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:2800-2804(1990).
Hammani K.,et al.J. Biol. Chem. 271:25498-25505(1996).
Malik K.,et al.Submitted (AUG-1990) to the EMBL/GenBank/DDBJ databases.
Stetler-Stevenson W.G.,et al.J. Biol. Chem. 264:17374-17378(1989).

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$ 467.50
Cat# ALS13261
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