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CNP / CNPase Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P09543 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 48kDa |
| Dilution | IHC-P (10 µg/ml), WB (1:500-1:3000), |
| Gene ID | 1267 |
|---|---|
| Other Names | 2', 3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, CNPase, 3.1.4.37, CNP |
| Target/Specificity | Human CNP. Predicted cross-reactivity based on amino acid sequence homology: mouse (82%), rat (84%), bovine (89%), monkey (97%). |
| Reconstitution & Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| Precautions | CNP / CNPase Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CNP (HGNC:2158) |
|---|---|
| Function | Catalyzes the formation of 2'-nucleotide products from 2',3'- cyclic substrates (By similarity). May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin (By similarity). |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:P16330}; Lipid- anchor {ECO:0000250|UniProtKB:P16330}. Melanosome. Note=Firmly bound to membrane structures of brain white matter. {ECO:0000250|UniProtKB:P16330} |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
References
Thompson R.J.,et al.Biochem. Soc. Trans. 20:621-626(1992).
Kurihara T.,et al.Biochem. Biophys. Res. Commun. 152:837-842(1988).
Monoh K.,et al.Gene 129:297-301(1993).
Douglas A.J.,et al.Ann. Hum. Genet. 56:243-254(1992).
Zody M.C.,et al.Nature 440:1045-1049(2006).
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