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SYP / Synaptophysin Antibody (clone 7H12)

Mouse Monoclonal Antibody

     
  • IHC - SYP / Synaptophysin Antibody (clone 7H12) ALS13204
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  • IHC - SYP / Synaptophysin Antibody (clone 7H12) ALS13204
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  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P08247
Reactivity Human, Rat
Host Mouse
Clonality Monoclonal
Clone Names 7H12
Calculated MW 34kDa
Dilution IHC-P (1:200), WB (1:500-1:2000),
Additional Information
Gene ID 6855
Other Names Synaptophysin, Major synaptic vesicle protein p38, SYP
Target/Specificity Human SYP
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsSYP / Synaptophysin Antibody (clone 7H12) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SYP
Function Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
Cellular Location Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Synapse, synaptosome
Tissue Location Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3 (PubMed:8838578). Expressed in the putamen (at protein level) (PubMed:17296554)
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).

References

Suedhof T.C.,et al.Nucleic Acids Res. 15:9607-9607(1987).
Oezcelik T.,et al.Am. J. Hum. Genet. 47:551-561(1990).
Fisher S.E.,et al.Genomics 45:340-347(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).

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$ 467.50
Cat# ALS13204
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