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CMA1 / MCT1 / Chymase Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | P23946 |
| Reactivity | Human, Monkey |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 27kDa |
| Dilution | IHC-P (1.5-3.75 µg/ml) |
| Gene ID | 1215 |
|---|---|
| Other Names | Chymase, 3.4.21.39, Alpha-chymase, Mast cell protease I, CMA1, CYH, CYM |
| Target/Specificity | Human CMA1 / Mast Cell Chymase. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | CMA1 / MCT1 / Chymase Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CMA1 |
|---|---|
| Synonyms | CYH, CYM |
| Function | Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. |
| Cellular Location | Secreted. Cytoplasmic granule. Note=Mast cell granules |
| Tissue Location | Mast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
References
Caughey G.H.,et al.J. Biol. Chem. 266:12956-12963(1991).
Urata H.,et al.J. Biol. Chem. 266:17173-17179(1991).
Schechter N.M.,et al.J. Immunol. 152:4062-4069(1994).
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
Heilig R.,et al.Nature 421:601-607(2003).
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