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SDC1 / Syndecan 1 / CD138 Antibody (clone DL-101)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IHC-F, FC |
|---|---|
| Primary Accession | P18827 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | DL-101 |
| Calculated MW | 32kDa |
| Dilution | IHC-Fr, IHC-P (20 µg/ml), |
| Gene ID | 6382 |
|---|---|
| Other Names | Syndecan-1, SYND1, CD138, SDC1, SDC |
| Reconstitution & Storage | Store at 4°C, avoid repeated freeze thaw cycles. |
| Precautions | SDC1 / Syndecan 1 / CD138 Antibody (clone DL-101) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SDC1 (HGNC:10658) |
|---|---|
| Synonyms | SDC |
| Function | Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity). Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway (By similarity). |
| Cellular Location | Membrane; Single-pass type I membrane protein. Secreted Secreted, extracellular exosome Note=Shedding of the ectodomain produces a soluble form |
| Tissue Location | Detected in placenta (at protein level) (PubMed:32337544). Detected in fibroblasts (at protein level) (PubMed:36213313). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.
References
Lories V.,et al.J. Biol. Chem. 267:1116-1122(1992).
Mali M.,et al.J. Biol. Chem. 265:6884-6889(1990).
Mennerich D.,et al.Eur. J. Cancer 40:1373-1382(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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