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IGFBP6 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P24592 |
| Reactivity | Human, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 25kDa |
| Dilution | ELISA (1:32000), IHC-P (5 µg/ml), WB (0.5-1.5 µg/ml) |
| Gene ID | 3489 |
|---|---|
| Other Names | Insulin-like growth factor-binding protein 6, IBP-6, IGF-binding protein 6, IGFBP-6, IGFBP6, IBP6 |
| Target/Specificity | Human IGFBP6. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | IGFBP6 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IGFBP6 (HGNC:5475) |
|---|---|
| Synonyms | IBP6 |
| Function | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration (PubMed:24003225). |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
References
Kiefer M.C.,et al.J. Biol. Chem. 266:9043-9049(1991).
Ehrenborg E.,et al.Mamm. Genome 10:376-380(1999).
Shimasaki S.,et al.Mol. Endocrinol. 5:938-948(1991).
Zapf J.,et al.J. Biol. Chem. 265:14892-14898(1990).
Roghani M.,et al.FEBS Lett. 255:253-258(1989).
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