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SELPLG / PSGL-1 / CD162 Antibody (clone HECA-452)

Rat Monoclonal Antibody

     
  • IHC - SELPLG / PSGL-1 / CD162 Antibody (clone HECA-452) ALS13027
    Anti-SELPLG / CD162 antibody IHC of human spleen.
    detail
  • IHC - SELPLG / PSGL-1 / CD162 Antibody (clone HECA-452) ALS13027
    Anti-SELPLG / CD162 antibody IHC of human tonsil.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
IHC-P, FC
Primary Accession Q14242
Reactivity Human, Mouse
Host Rat
Clonality Monoclonal
Clone Names HECA-452
Calculated MW 43kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 6404
Other Names P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162, SELPLG
Reconstitution & Storage +4°C, avoid freezing
PrecautionsSELPLG / PSGL-1 / CD162 Antibody (clone HECA-452) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SELPLG
Function A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.
Cellular Location Membrane; Single-pass type I membrane protein.
Tissue Location Expressed on neutrophils, monocytes and most lymphocytes
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.

References

Veldman G.M.,et al.J. Biol. Chem. 270:16470-16475(1995).
Sako D.,et al.Cell 75:1179-1186(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Moore K.L.,et al.J. Biol. Chem. 269:23318-23327(1994).

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$ 467.50
Cat# ALS13027
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