GFAP Antibody (clone GF-01)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, ICC, IP |
---|---|
Primary Accession | P14136 |
Reactivity | Human, Pig, Cat |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | GF-01 |
Calculated MW | 50kDa |
Dilution | IHC-P (10 µg/ml) |
Gene ID | 2670 |
---|---|
Other Names | Glial fibrillary acidic protein, GFAP, GFAP |
Target/Specificity | Reacts with GFAP molecules. GFAP is the principal marker of astroglial cells in the central nervous system; it is specifically expressed in satellite cells in peripheral ganglia and in non myelinating Schwann cells in peripheral nerves. The GFAP prot ... |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | GFAP Antibody (clone GF-01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GFAP |
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Function | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
Cellular Location | Cytoplasm. Note=Associated with intermediate filaments |
Tissue Location | Expressed in cells lacking fibronectin. |
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Provided below are standard protocols that you may find useful for product applications.
Background
GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
References
Reeves S.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:5178-5182(1989).
Brenner M.,et al.Brain Res. Mol. Brain Res. 7:277-286(1990).
Bongcam-Rudloff E.,et al.Cancer Res. 51:1553-1560(1991).
Kumanishi T.,et al.Acta Neuropathol. 83:569-578(1992).
Isaacs A.,et al.Genomics 51:152-154(1998).
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