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SCG10 / STMN2 Antibody

Goat Polyclonal Antibody

     
  • IHC - SCG10 / STMN2 Antibody ALS12745
    Anti-STMN2 antibody IHC of human small intestine, myenteric plexus.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q93045
Reactivity Human, Mouse, Rat, Rabbit, Hamster, Monkey, Chicken, Horse, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 21kDa
Dilution ELISA (1:32000), IHC-P (5 µg/ml), WB (0.1-1 µg/ml)
Additional Information
Gene ID 11075
Other Names Stathmin-2, Superior cervical ganglion-10 protein, Protein SCG10, STMN2, SCG10, SCGN10
Target/Specificity Human STMN2.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsSCG10 / STMN2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STMN2
Synonyms SCG10, SCGN10
Function Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity).
Cellular Location Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Golgi apparatus. Endosome. Cell projection, lamellipodium. Note=Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane- bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity). Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia.
Tissue Location Neuron specific.
Research Areas
Citations (0)
citation

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Background

Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity).

References

Okazaki T.,et al.Neurobiol. Aging 16:883-894(1995).
Fujiwara T.,et al.Submitted (APR-1995) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 467.50
Cat# ALS12745
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