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HGF Antibody (clone 7-2)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P14210 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 7-2 |
| Calculated MW | 83kDa |
| Dilution | IHC-P (10 µg/ml) |
| Gene ID | 3082 |
|---|---|
| Other Names | Hepatocyte growth factor, Hepatopoietin-A, Scatter factor, SF, Hepatocyte growth factor alpha chain, Hepatocyte growth factor beta chain, HGF, HPTA |
| Target/Specificity | Reacts with human HGF and to a lesser extent, mouse by Western Blot. |
| Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | HGF Antibody (clone 7-2) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HGF |
|---|---|
| Synonyms | HPTA |
| Function | Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types (PubMed:20624990). Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (PubMed:15167892, PubMed:20977675). Activates MAPK signaling following TMPRSS13 cleavage and activation (PubMed:20977675). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.
References
Miyazawa K.,et al.Biochem. Biophys. Res. Commun. 163:967-973(1989).
Nakamura T.,et al.Nature 342:440-443(1989).
Seki T.,et al.Biochem. Biophys. Res. Commun. 172:321-327(1990).
Seki T.,et al.Gene 102:213-219(1991).
Miyazawa K.,et al.Eur. J. Biochem. 197:15-22(1991).
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