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CRLF2 / TSLPR Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | Q9HC73 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 42kDa |
| Dilution | IHC-P (5 µg/ml), WB (1 µg/ml), |
| Gene ID | 64109 |
|---|---|
| Other Names | Cytokine receptor-like factor 2, Cytokine receptor-like 2, IL-XR, Thymic stromal lymphopoietin protein receptor, TSLP receptor, CRLF2, CRL2, ILXR, TSLPR |
| Target/Specificity | a 19 amino acid peptide from near the center of human TSLP-R |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | CRLF2 / TSLPR Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CRLF2 |
|---|---|
| Synonyms | CRL2, ILXR, TSLPR |
| Function | Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system. |
| Cellular Location | [Isoform 1]: Cell membrane; Single- pass type I membrane protein |
| Tissue Location | Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes Weakly expressed in T-cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system.
References
Zhang W.,et al.Biochem. Biophys. Res. Commun. 281:878-883(2001).
Tonozuka Y.,et al.Cytogenet. Cell Genet. 93:23-25(2001).
Reche P.A.,et al.J. Immunol. 167:336-343(2001).
Li T.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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