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PLIN1 / Perilipin Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | O60240 |
| Reactivity | Human, Monkey |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 56kDa |
| Dilution | ELISA (1:128000), IHC-P (2 µg/ml), WB (0.01 µg/ml) |
| Gene ID | 5346 |
|---|---|
| Other Names | Perilipin-1, Lipid droplet-associated protein, PLIN1, PERI, PLIN |
| Target/Specificity | Human PLIN1 / Perilipin. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | PLIN1 / Perilipin Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PLIN1 |
|---|---|
| Synonyms | PERI, PLIN |
| Function | Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels. |
| Cellular Location | Endoplasmic reticulum. Lipid droplet. Note=Lipid droplet surface-associated. |
| Tissue Location | Detected in adipocytes from white adipose tissue (at protein level) (PubMed:27832861). Detected in visceral adipose tissue and mammary gland (PubMed:9521880) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone- sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.
References
Nishiu J.,et al.Genomics 48:254-257(1998).
Zody M.C.,et al.Nature 440:671-675(2006).
Gandotra S.,et al.N. Engl. J. Med. 364:740-748(2011).
Grahn T.H.,et al.Biochem. Biophys. Res. Commun. 432:296-301(2013).
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