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TS / Thymidylate Synthase Antibody
Sheep Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E, IP |
|---|---|
| Primary Accession | P04818 |
| Reactivity | Human |
| Host | Sheep |
| Clonality | Polyclonal |
| Calculated MW | 36kDa |
| Dilution | IHC-P (5 µg/ml) |
| Gene ID | 7298 |
|---|---|
| Other Names | Thymidylate synthase, TS, TSase, 2.1.1.45, TYMS, TS |
| Target/Specificity | Recombinant human Thymidylate Synthase (36 kD) produced in E. coli. |
| Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. |
| Precautions | TS / Thymidylate Synthase Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TYMS (HGNC:12441) |
|---|---|
| Synonyms | TS |
| Function | Catalyzes the reductive methylation of 2'-deoxyuridine 5'- monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1- carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway. |
| Cellular Location | Nucleus. Cytoplasm. Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
References
Takeishi K.,et al.Nucleic Acids Res. 13:2035-2043(1985).
Kaneda S.,et al.J. Biol. Chem. 265:20277-20284(1990).
Hisatomi H.,et al.Cancer Lett. 193:127-131(2003).
Shichijo S.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
Nusbaum C.,et al.Nature 437:551-555(2005).
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