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MDH1 Antibody
Sheep Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E, IP |
|---|---|
| Primary Accession | P40925 |
| Reactivity | Human, Pig |
| Host | Sheep |
| Clonality | Polyclonal |
| Calculated MW | 36kDa |
| Dilution | IHC-P (5 µg/ml) |
| Gene ID | 4190 |
|---|---|
| Other Names | Malate dehydrogenase, cytoplasmic, 1.1.1.37, Cytosolic malate dehydrogenase, Diiodophenylpyruvate reductase, 1.1.1.96, MDH1, MDHA |
| Target/Specificity | Malate Dehydrogenase |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | MDH1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MDH1 {ECO:0000303|PubMed:34012073, ECO:0000312|HGNC:HGNC:6970} |
|---|---|
| Function | Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH (PubMed:2449162, PubMed:3052244). Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation (PubMed:31538237). Catalyzes the reduction of 2-oxoglutarate to 2- hydroxyglutarate, leading to elevated reactive oxygen species (ROS) (PubMed:34012073). |
| Cellular Location | Cytoplasm, cytosol. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Tanaka T.,et al.Genomics 32:128-130(1996).
Lo A.S.Y.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
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