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CDC7 Antibody (Kinase Domain)

Rabbit Polyclonal Antibody

     
  • IHC - CDC7 Antibody (Kinase Domain) ALS10922
    Anti-CDC7 antibody IHC of human Skin, Melanoma.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession O00311
Reactivity Human, Rabbit, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 64kDa
Dilution IHC-P (6.5 µg/ml)
Additional Information
Gene ID 8317
Other Names Cell division cycle 7-related protein kinase, CDC7-related kinase, HsCdc7, huCdc7, 2.7.11.1, CDC7, CDC7L1
Target/Specificity Human CDC7. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsCDC7 Antibody (Kinase Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDC7 (HGNC:1745)
Synonyms CDC7L1
Function Kinase involved in initiation of DNA replication. Phosphorylates critical substrates that regulate the G1/S phase transition and initiation of DNA replication, such as MCM proteins and CLASPIN.
Cellular Location Nucleus.
Volume 50 µl
Research Areas
Citations (0)
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Background

Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.

References

Sato N.,et al.EMBO J. 16:4340-4351(1997).
Hess G.F.,et al.Gene 211:133-140(1998).
Jiang W.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:14320-14325(1997).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 467.50
Cat# ALS10922
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