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SLC5A4 / SGLT2 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q9NY91 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 72kDa |
| Dilution | IHC-P (20 µg/ml) |
| Gene ID | 6527 |
|---|---|
| Other Names | Low affinity sodium-glucose cotransporter, Sodium/glucose cotransporter 3, Na(+)/glucose cotransporter 3, Solute carrier family 5 member 4, SLC5A4, SAAT1, SGLT2 |
| Target/Specificity | Human SLC5A4. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | SLC5A4 / SGLT2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC5A4 {ECO:0000303|PubMed:13130073} |
|---|---|
| Function | Does not function as sodium/D-glucose symporter (PubMed:13130073, PubMed:20421923, PubMed:22766068). However, may function as a D-glucose sensor by generating a D-glucose-induced depolarization which is pH-independent, Na(+)-dependent at neutral pH and probably H(+)-dependent at acidic pH (PubMed:13130073, PubMed:17110502, PubMed:20421923, PubMed:22766068). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in skeletal muscle, where it may localize to the neuromuscular junction (at protein level) (PubMed:13130073) Expressed in small intestine where it may localize to cholinergic neurons of the submucosal plexus and myenteric plexus (at protein level) (PubMed:13130073). Detected in kidney (at protein level) (PubMed:22766068). |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Sodium-dependent glucose transporter.
References
Gorboulev V.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Dunham I.,et al.Nature 402:489-495(1999).
Poppe R.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
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