GPR61 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E |
---|---|
Primary Accession | Q9BZJ8 |
Reactivity | Human, Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 49kDa |
Dilution | IHC-P (10 µg/ml) |
Gene ID | 83873 |
---|---|
Other Names | Probable G-protein coupled receptor 61, Biogenic amine receptor-like G-protein coupled receptor, GPR61, BALGR |
Target/Specificity | Human GPR61. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | GPR61 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GPR61 |
---|---|
Synonyms | BALGR {ECO:0000303|PubMed:11690637}, GPC |
Function | Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway (PubMed:28827538). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538). May be involved in the regulation of food intake and body weight (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi- pass membrane protein. Note=Colocalizes with ARRB2/beta- arrestin-2 in the endosome (PubMed:28827538) |
Tissue Location | Expressed in brain; detected in frontal and temporal lobes, occipital pole, amygdala and hippocampus (PubMed:11690637, PubMed:29226084). Also expressed in testis (PubMed:11690637, PubMed:29226084) and T cells, B cells, and monocyte (PubMed:29226084). Low expression in many other tissues (PubMed:11690637, PubMed:29226084). Widely expressed in the hippocampus (at protein level). |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Orphan receptor.
References
Lee D.K.,et al.Brain Res. Mol. Brain Res. 86:13-22(2001).
Cikos S.,et al.Biochim. Biophys. Acta 1521:66-72(2001).
Takeda S.,et al.FEBS Lett. 520:97-101(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
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