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DRD2 / Dopamine Receptor D2 Antibody (Cytoplasmic Domain)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | P14416 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 51kDa |
| Dilution | IHC-P (5-10 µg/ml) |
| Gene ID | 1813 |
|---|---|
| Other Names | D(2) dopamine receptor, Dopamine D2 receptor, DRD2 |
| Target/Specificity | Human DRD2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ZNF57 (42%). |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | DRD2 / Dopamine Receptor D2 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DRD2 |
|---|---|
| Function | Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (PubMed:21645528). Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5 (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein |
| Tissue Location | [Isoform 1]: Expressed in the anterior pituitary gland. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.
References
Selbie L.A.,et al.DNA 8:683-689(1989).
Dal-Toso R.,et al.EMBO J. 8:4025-4034(1989).
Robakis N.K.,et al.Nucleic Acids Res. 18:1299-1299(1990).
Grandy D.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:9762-9766(1989).
Stormann T.M.,et al.Mol. Pharmacol. 37:1-6(1990).
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