TRH Receptor / TRHR Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P34981 |
Reactivity | Human, Pig, Sheep, Horse, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 45kDa |
Dilution | IHC-P (20 µg/ml) |
Gene ID | 7201 |
---|---|
Other Names | Thyrotropin-releasing hormone receptor, TRH-R, Thyroliberin receptor, TRHR |
Target/Specificity | Human TRH Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | TRH Receptor / TRHR Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TRHR |
---|---|
Function | Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
References
Matre V.,et al.Biochem. Biophys. Res. Commun. 195:179-185(1993).
Yamada M.,et al.Biochem. Biophys. Res. Commun. 195:737-745(1993).
Duthie S.M.,et al.Mol. Cell. Endocrinol. 95:R11-R15(1993).
Hinuma S.,et al.Biochim. Biophys. Acta 1219:251-259(1994).
Iwasaki T.,et al.J. Biol. Chem. 271:22183-22188(1996).
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