Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
GRM5 / MGLUR5 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P41594 |
| Reactivity | Human, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 132kDa |
| Dilution | IHC-P (16 µg/ml) |
| Gene ID | 2915 |
|---|---|
| Other Names | Metabotropic glutamate receptor 5, mGluR5, GRM5, GPRC1E, MGLUR5 |
| Target/Specificity | Human GRM5 / MGLUR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CDC42EP5 (69%). |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | GRM5 / MGLUR5 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GRM5 |
|---|---|
| Synonyms | GPRC1E, MGLUR5 |
| Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol- calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
References
Minakami R.,et al.Biochem. Biophys. Res. Commun. 199:1136-1143(1994).
Katsuki F.,et al.Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases.
Levinthal C.,et al.Abstr. - Soc. Neurosci. 25:976-976(1999).
Taylor T.D.,et al.Nature 440:497-500(2006).
Minakami R.,et al.Biochem. Biophys. Res. Commun. 194:622-627(1993).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
