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S1PR4 / SIP4 / EDG6 Antibody (Cytoplasmic Domain)

Rabbit Polyclonal Antibody

     
  • IHC - S1PR4 / SIP4 / EDG6 Antibody (Cytoplasmic Domain) ALS10023
    Anti-S1PR4 / EDG6 antibody IHC of human spleen.
    detail
  • IHC - S1PR4 / SIP4 / EDG6 Antibody (Cytoplasmic Domain) ALS10023
    Anti-S1PR4 / EDG6 antibody IHC of human lymph node.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession O95977
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 42kDa
Dilution IHC-P (9.6 µg/ml)
Additional Information
Gene ID 8698
Other Names Sphingosine 1-phosphate receptor 4, S1P receptor 4, S1P4, Endothelial differentiation G-protein coupled receptor 6, Sphingosine 1-phosphate receptor Edg-6, S1P receptor Edg-6, S1PR4, EDG6
Target/Specificity Human S1PR4 / EDG6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsS1PR4 / SIP4 / EDG6 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name S1PR4
Synonyms EDG6
Function Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung
Research Areas
Citations (0)
citation

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Background

Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.

References

Graeler M.H.,et al.Genomics 53:164-169(1998).
Kopatz S.A.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Yamazaki Y.,et al.Biochem. Biophys. Res. Commun. 268:583-589(2000).
Van Brocklyn J.R.,et al.Blood 95:2624-2629(2000).

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$ 467.50
Cat# ALS10023
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