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GTF2E1 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P29083 |
| Other Accession | NM_005513, NP_005504 |
| Reactivity | Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 49kDa |
| Gene ID | 2960 |
|---|---|
| Alias Symbol | FE, TF2E1, TFIIE-A |
| Other Names | General transcription factor IIE subunit 1, General transcription factor IIE 56 kDa subunit, Transcription initiation factor IIE subunit alpha, TFIIE-alpha, GTF2E1, TF2E1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-GTF2E1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | GTF2E1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GTF2E1 |
|---|---|
| Synonyms | TF2E1 |
| Function | Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. |
| Cellular Location | Nucleus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
References
Peterson M.G.,et al.Nature 354:369-373(1991).
Ohkuma Y.,et al.Nature 354:398-401(1991).
Bienvenut W.V.,et al.Submitted (JAN-2010) to UniProtKB.
Hisatake K.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:8195-8199(1995).
Di Valentin E.,et al.Biol. Chem. 386:255-267(2005).
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