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TNFRSF25 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q93038 |
| Other Accession | NM_148967, NP_683868 |
| Reactivity | Human, Mouse, Rat, Rabbit, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 38kDa |
| Gene ID | 8718 |
|---|---|
| Alias Symbol | APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR |
| Other Names | Tumor necrosis factor receptor superfamily member 25, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, Death receptor 3, Lymphocyte-associated receptor of death, LARD, Protein WSL, Protein WSL-1, TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-TNFRSF25 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | TNFRSF25 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TNFRSF25 |
|---|---|
| Synonyms | APO3, DDR3, DR3, TNFRSF12, WSL, WSL1 |
| Function | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. |
| Cellular Location | [Isoform 1]: Cell membrane; Single-pass type I membrane protein [Isoform 9]: Cell membrane; Single-pass type I membrane protein [Isoform 3]: Secreted. [Isoform 5]: Secreted. [Isoform 7]: Secreted. [Isoform 10]: Secreted. |
| Tissue Location | Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
References
Kitson J.,et al.Nature 384:372-375(1996).
Chinnaiyan A.M.,et al.Science 274:990-992(1996).
Degli-Esposti M.A.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
Marsters S.A.,et al.Curr. Biol. 6:1669-1676(1996).
Screaton G.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:4615-4619(1997).
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