DND1 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8IYX4 |
Other Accession | NP_919225 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 38kDa |
Gene ID | 373863 |
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Alias Symbol | DND1, RBMS4, |
Other Names | Dead end protein homolog 1, RNA-binding motif, single-stranded-interacting protein 4, DND1, RBMS4 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-DND1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
Precautions | DND1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DND1 |
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Synonyms | RBMS4 |
Function | RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence- specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity). |
Cellular Location | Nucleus. Cytoplasm. Note=Perinuclear germ granules, also called germ plasm or chromatoid body. Colocalizes in perinuclear sites with APOBEC3 (By similarity). |
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Provided below are standard protocols that you may find useful for product applications.
Background
RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity).
References
Weidinger G.,et al.Curr. Biol. 13:1429-1434(2003).
Kedde M.,et al.Cell 131:1273-1286(2007).
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