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NDNF Antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - NDNF Antibody - N-terminal region AI15674

    Host: Rabbit
    Target Name: NDNF
    Sample Tissue: Jurkat Whole cell lysate
    s
    Antibody Dilution: 1.0μg/ml
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q8TB73
Other Accession NM_024574, NP_078850
Reactivity Human, Pig
Predicted Human, Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 62kDa
Additional Information
Gene ID 79625
Alias Symbol C4orf31
Other Names Protein NDNF, Neuron-derived neurotrophic factor, NDNF, C4orf31
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-NDNF antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsNDNF Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NDNF
Synonyms C4orf31
Function Secretory protein that plays a role in various cellular processes (PubMed:20969804, PubMed:24706764, PubMed:31883645). Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus (PubMed:31883645). Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system (PubMed:20969804, PubMed:31883645). May also act through the regulation of growth factors activity and downstream signaling (PubMed:31883645). Also regulates extracellular matrix assembly and cell adhesiveness (By similarity). Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms (PubMed:24706764).
Cellular Location Secreted
Tissue Location Expressed in neurons along the gonadotropin- releasing hormone (GnRH) expressing neurons migratory route
Research Areas
Citations (0)
citation

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References

Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Kuang X.L.,et al.BMC Neurosci. 11:137-137(2010).

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$ 389.00
Cat# AI15674
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