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HSD17B13 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q7Z5P4 |
| Other Accession | NM_178135, NP_835236 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 33kDa |
| Gene ID | 345275 |
|---|---|
| Alias Symbol | NIIL497, SCDR9, SDR16C3 |
| Other Names | 17-beta-hydroxysteroid dehydrogenase 13, 17-beta-HSD 13, 1.1.-.-, Short-chain dehydrogenase/reductase 9, HSD17B13, SCDR9 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-HSD17B13 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | HSD17B13 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HSD17B13 (HGNC:18685) |
|---|---|
| Function | Plays a pivotal role in hepatic lipid metabolism (PubMed:29562163). In vitro, it catalyzes the oxidation of a variety of lipid substrates, including 17beta-estradiol, retinol, retinal, and leukotriene B4 (PubMed:29562163, PubMed:30415504, PubMed:32973038). |
| Cellular Location | [Isoform 2]: Lipid droplet. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8VCR2}. Note=Redistributed from the endoplasmic reticulum to lipids droplets in the cell upon induction of lipids droplet formation. {ECO:0000250|UniProtKB:Q8VCR2} |
| Tissue Location | Highly expressed in the liver (PubMed:29562163). Also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Zhong H.,et al.Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
Liu S.,et al.Acta Biochim. Pol. 54:213-218(2007).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Yamada S.,et al.Oncogene 23:5901-5911(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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