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UQCRQ Antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - UQCRQ Antibody - middle region AI15469

    WB Suggested Anti-UQCRQ Antibody Titration: 1.0 μg/ml
    Positive Control: Fetal Liver
    detail
  • WB - UQCRQ Antibody - middle region AI15469

    Host:Rabbit
    Target Name:UQCRQ
    Sample Tissue:Human Adult Placenta
    Antibody Dilution: 1.0μg/ml
    detail
  • WB - UQCRQ Antibody - middle region AI15469

    Host:Rabbit
    Target Name:UQCRQ
    Sample Tissue:Human MCF7
    Antibody Dilution: 1.0μg/mlUQCRQ is supported by BioGPS gene expression data to be expressed in MCF7
    detail
  • WB - UQCRQ Antibody - middle region AI15469

    Host:Rabbit
    Target Name:UQCRQ
    Sample Tissue:Human 721_B
    Antibody Dilution: 1.0μg/mlUQCRQ is supported by BioGPS gene expression data to be expressed in 721_B
    detail
  • WB - UQCRQ Antibody - middle region AI15469

    Host:Rabbit
    Target Name:UQCRQ
    Sample Tissue:Human Hela
    Antibody Dilution: 1.0μg/mlUQCRQ is supported by BioGPS gene expression data to be expressed in HeLa
    detail
  • WB - UQCRQ Antibody - middle region AI15469
    Host:Rabbit Target Name:UQCRQ Sample Tissue:Human Fetal Kidney Antibody Dilution: 1.0ug/ml
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O14949
Other Accession NM_014402, NP_055217
Reactivity Human, Mouse, Rat, Rabbit, Pig, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 10kDa
Additional Information
Gene ID 27089
Alias Symbol QCR8, QP-C, QPC, UQCR7
Other Names Cytochrome b-c1 complex subunit 8, Complex III subunit 8, Complex III subunit VIII, Ubiquinol-cytochrome c reductase complex 9.5 kDa protein, Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C, UQCRQ
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-UQCRQ antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsUQCRQ Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UQCRQ
Function Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
Cellular Location Mitochondrion inner membrane {ECO:0000250|UniProtKB:P08525}; Single-pass membrane protein {ECO:0000250|UniProtKB:P08525}
Research Areas
Citations (0)
citation

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References

Fujiwara T.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
Schaegger H.,et al.Methods Enzymol. 260:82-96(1995).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Barel O.,et al.Am. J. Hum. Genet. 82:1211-1216(2008).

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$ 389.00
Cat# AI15469
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