B3GAT1 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9P2W7 |
Other Accession | NM_054025, NP_473366 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 37kDa |
Gene ID | 27087 |
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Alias Symbol | CD57, GLCATP, GLCUATP, HNK1, LEU7, NK-1, NK1 |
Other Names | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, 2.4.1.135, Beta-1, 3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:glycoprotein beta-1, 3-glucuronyltransferase, GlcUAT-P, B3GAT1, GLCATP |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-B3GAT1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | B3GAT1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | B3GAT1 (HGNC:921) |
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Synonyms | GLCATP |
Function | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo- fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl- sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
Cellular Location | [Isoform 1]: Golgi apparatus membrane {ECO:0000250|UniProtKB:O35789}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:O35789}. Secreted {ECO:0000250|UniProtKB:O35789} |
Tissue Location | Mainly expressed in the brain. |
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Provided below are standard protocols that you may find useful for product applications.
References
Mitsumoto Y.,et al.Genomics 65:166-173(2000).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Kakuda S.,et al.J. Biol. Chem. 279:22693-22703(2004).
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