SELPLG Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q14242 |
Other Accession | NM_003006, NP_002997 |
Reactivity | Human, Rat, Bovine, Guinea Pig, Dog |
Predicted | Human, Rat, Pig, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 39kDa |
Gene ID | 6404 |
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Alias Symbol | CD162, CLA, PSGL-1, PSGL1 |
Other Names | P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162, SELPLG |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-SELPLG antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | SELPLG Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SELPLG |
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Function | A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture. |
Cellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Location | Expressed on neutrophils, monocytes and most lymphocytes |
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Provided below are standard protocols that you may find useful for product applications.
References
Veldman G.M.,et al.J. Biol. Chem. 270:16470-16475(1995).
Sako D.,et al.Cell 75:1179-1186(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Moore K.L.,et al.J. Biol. Chem. 269:23318-23327(1994).
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