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LILRA3 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8N6C8 |
| Other Accession | NM_006865, NP_006856 |
| Reactivity | Human, Bovine |
| Predicted | Human, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 45kDa |
| Gene ID | 11026 |
|---|---|
| Alias Symbol | CD85E, HM31, HM43, ILT6, LIR-4, LIR4, e3 |
| Other Names | Leukocyte immunoglobulin-like receptor subfamily A member 3, CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4, Monocyte inhibitory receptor HM43/HM31, CD85e, LILRA3, ILT6, LIR4 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-LILRA3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | LILRA3 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LILRA3 |
|---|---|
| Synonyms | ILT6, LIR4 |
| Function | Acts as a soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes. |
| Cellular Location | Secreted. |
| Tissue Location | Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Arm J.P.,et al.J. Immunol. 159:2342-2349(1997).
Borges L.,et al.J. Immunol. 159:5192-5196(1997).
Samaridis J.,et al.Eur. J. Immunol. 27:660-665(1997).
Grimwood J.,et al.Nature 428:529-535(2004).
Norman P.J.,et al.Immunogenetics 55:165-171(2003).
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