FCER2 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P06734 |
Other Accession | NM_002002, NP_001993 |
Reactivity | Human |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 35kDa |
Gene ID | 2208 |
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Alias Symbol | CD23, CD23A, CLEC4J, FCE2, IGEBF |
Other Names | Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, CD23, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form, FCER2, CD23A, CLEC4J, FCE2, IGEBF |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-FCER2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | FCER2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FCER2 |
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Synonyms | CD23A, CLEC4J, FCE2, IGEBF |
Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells (PubMed:2167225). On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine- nitric oxide pathway (PubMed:7544003). |
Cellular Location | Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid-anchor. Secreted. Note=Also exists as a soluble excreted form, sCD23 |
Tissue Location | Detected in urine (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
References
Ikuta K.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:819-823(1987).
Kikutani H.,et al.Cell 47:657-665(1986).
Luedin C.,et al.EMBO J. 6:109-114(1987).
Grimwood J.,et al.Nature 428:529-535(2004).
Yokota A.,et al.Cell 55:611-618(1988).
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