PRKCSH antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | P14314 |
Other Accession | NM_002743, NP_002734 |
Reactivity | Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 59kDa |
Gene ID | 5589 |
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Alias Symbol | AGE-R2, G19P1, PCLD, PLD1 |
Other Names | Glucosidase 2 subunit beta, 80K-H protein, Glucosidase II subunit beta, Protein kinase C substrate 60.1 kDa protein heavy chain, PKCSH, PRKCSH, G19P1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-PRKCSH antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | PRKCSH antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PRKCSH {ECO:0000303|PubMed:28375157, ECO:0000312|HGNC:HGNC:9411} |
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Function | Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (PubMed:10929008). Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity). |
Cellular Location | Endoplasmic reticulum {ECO:0000255|PROSITE- ProRule:PRU10138, ECO:0000305|PubMed:10929008} |

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Provided below are standard protocols that you may find useful for product applications.
References
Sakai K.,et al.Genomics 5:309-315(1989).
Ophoff R.A.,et al.Eur. J. Hum. Genet. 4:321-328(1996).
Pelletier M.F.,et al.Glycobiology 10:815-827(2000).
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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